Accuracy of artificial intelligence in orthodontic extraction treatment planning: a systematic review and meta analysis
AI Models Demonstrate Promising 70% Sensitivity and 90% Specificity in Orthodontic Extraction Prediction
A systematic review and meta-analysis of seven studies, encompassing 6,261 patients, reveals that AI models, particularly CNN-based ones, offer moderate to high diagnostic accuracy in predicting the need for orthodontic extractions. Despite high heterogeneity, these models represent a significant advancement in dental treatment planning, suggesting potential for increased accuracy and standardization.
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AI models achieved a pooled sensitivity of 70%, indicating a moderate to high ability to correctly identify cases requiring extractions. This finding suggests a significant potential for AI in improving diagnostic accuracy in orthodontic treatment planning, although individual model performance can vary.
| Model Type | Sensitivity (95% CI) | Specificity (95% CI) | Heterogeneity (I²) |
|---|---|---|---|
| CNN (ResNet) | 0.758 (0.693-0.822) | 0.941 (0.923-0.960) | 0.0% |
| CNN (VGG) | 0.824 (0.767-0.882) | 0.931 (0.911-0.951) | 0.0% |
| Random Forest | 0.731 (0.637-0.824) | 0.724 (0.622-0.825) | 91.1% |
| Neural Network (MLP) | 0.797 (0.666-0.927) | 0.794 (0.687-0.900) | 97.2% |
Impact of Disease Prevalence on Sensitivity
Meta-regression analysis revealed a statistically significant association between disease prevalence and sensitivity (β = 0.9923, p = 0.050). This suggests that studies with higher disease prevalence tended to report higher sensitivity values, potentially limiting the generalizability of models trained on over-represented outcomes. This highlights the need for balanced datasets in training AI models for broad applicability and robust performance across diverse patient populations.
Enterprise Process Flow: Study Selection
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